Exosomes and PDRN

Written By: SKINN In Dermatology, Date: Sat Jul 12 2025

Exosomes are tiny, bubble-like structures naturally released by cells in your body. They play a critical role in cell-to-cell communication actting like biological messengers. Exosomes are popular in regenerative medicine and aesthetic treatments.


PDRN (Polydeoxyribonucleotide) is a DNA fragment extracted primarily from salmon sperm cells and has powerful skin-repair and anti-inflammatory properties.


Clinical and Aesthetic Uses:

  1. Skin rejuvenation: boost collagen, repair damage, reduce inflammation
  2. Hair restoration: stimulate dormant follicles
  3. Wound healing: accelerate tissue repair
  4. Anti-aging: improve skin texture and reduce wrinkles


1. Skin Rejuvenation

Exosomes are used to revitalize tired, aging, or damaged skin by delivering growth factors, peptides, and genetic material that:

  1. Stimulate collagen and elastin production
  2. Improve skin texture and tone
  3. Reduce fine lines, wrinkles, and pigmentation
  4. Calm inflammation and redness

2. Hair Restoration

Exosomes are showing promising results in stimulating hair growth, especially in early to moderate hair thinning.

They work by:

  1. Activating dormant follicles
  2. Enhancing blood supply to the scalp
  3. Extending the growth phase of the hair cycle
  4. Reducing inflammation and scalp damage

3. Acne and Acne Scarring

Exosomes’ anti-inflammatory and regenerative effects help:

  1. Calm active acne
  2. Reduce acne-induced inflammation
  3. Support collagen remodeling to improve acne scars